TARGETING AKT IN CANCER FOR PRECISION THERAPY

Targeting Akt in cancer for precision therapy

Abstract Biomarkers-guided precision therapeutics has revolutionized the clinical development and administration of molecular-targeted anticancer agents.Tailored precision cancer therapy exhibits better response rate compared to unselective Pads treatment.Protein kinases have critical roles in cell signaling, metabolism, proliferation, survival and

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An Enhanced Flow-Thermo-Structural Modeling and Validation for the Integrated Analysis of a Film Cooling Nozzle Guide Vane

The target of this paper Spoon Rests is to develop an enhanced flow-thermo-structural (FTS) model with high computational accuracy, to perform the integrated analysis of film cooling nozzle guide vane (NGV).An efficient turbulence model and weak spring approach are utilized in the enhanced FTS model.In respect of the power balance principle of aero

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The Comparison of Chunking Methods to Enhance the Cognitive Capacity of Short-term Memory to Retain Textual Information among High School Students

Our short-term memory has a limited capacity of taking in information and retaining it the memory storage.However, this can be enhanced by various memory techniques especially dividing the information into smaller chunks.To investigate this memory enhancement strategy, this study compared the effectiveness of three chunking methods, namely One-Chun

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